Effect of antimicrobial peptides against P. falciparum cultured gametocytes.

Peptides (final concentration of 50 µM) were mixed with cultured P. falciparum gametocytes and membrane-fed to An. gambiae mosquitoes (performed at the Pasteur Institute, Paris). For each of three replicates, oocyst prevalence (number of oocyst positive mosquitoes, total number in parentheses) and oocyst intensity (mean number of oocysts present per gut, range in parentheses) were recorded. An equivalent volume of water without peptide was used for the control. N/S indicates non-significance.