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Mycobacterium thermoresistibile GyrB21 in complex with Redx03863

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Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6y8n
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资源简介:
Mycobacterium thermoresistibile GyrB21 in complex with Redx03863 Descriptor: 1,2-ETHANEDIOL, 4-[(1~{S},5~{R})-6-azanyl-3-azabicyclo[3.1.0]hexan-3-yl]-6-fluoranyl-~{N}-methyl-2-(2-methylpyrimidin-5-yl)oxy-9~{H}-pyrimido[4,5-b]indol-8-amine, DNA gyrase subunit B, ... Authors: Henderson, S.R, Stevenson, C.E.M, Malone, B, Zholnerovych, Y, Mitchenall, L.A, Pichowicz, M, McGarry, D.H, Cooper, I.R, Charrier, C, Salisbury, A, Lawson, D.M, Maxwell, A. Deposit date: 2020-03-05 Release date: 2020-08-12 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural and mechanistic analysis of ATPase inhibitors targeting mycobacterial DNA gyrase. J.Antimicrob.Chemother., 75, 2020
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2020-03-05
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