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Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters
Effects of polyomavirus SV40 microRNA on pathogenesis of viral infections in vivo are not known. Syrian golden hamsters are the small animal model for studies of SV40. We report here effects of SV40 m
Figshare2016-01-15 更新120
Hepatic gene expression in transgenic mice with conditional liver-specific expression of the SV40 17kT/LT oncoproteins
The SV40 large (LT) and small (st) antigens are produced from a single alternatively spliced pre-mRNA, that when co-expressed, transform a variety of cells in vitro and in vivo. However, 17kT, a rela
NIAID Data Ecosystem100
Expression of a Neuroendocrine Gene Signature in Gastric Tumor Cells from CEA 424 -SV40 Large T Antigen-Transgenic Mice Depends on SV40 Large T Antigen
BackgroundA large fraction of murine tumors induced by transgenic expression of SV40 large T antigen (SV40 TAg) exhibits a neuroendocrine phenotype. It is unclear whether SV40 TAg induces the neuroend
NIAID Data Ecosystem40
Global analysis of gene expression in REF52 cells expressing SV40 T antigens. Rattus norvegicus
SV40 transforms cells through the action of two oncoproteins, large T antigen and small t antigen. Small t antigen targets phosphatase PP2A, while large T antigen stimulates cell proliferation and sur
NIAID Data Ecosystem70
