mRNA expression data from skeletal muscle of type 2 diabetes. Homo sapiens

We used microarray technology to profile mRNA expression in the skeletal muscle of normal (NGT), glucose intolerant (IGT) and type 2 diabetic (DM) subjects. Groups were classified using WHO criteria and, importantly, the DM group were free of anti hypoglycaemic medication for one week prior to biopsy. Overall design: Total RNA was extracted from the vastus lateralis of normal (NGT), glucose intolerant (IGT) and type 2 diabetic (DM) subjects (n = 118 in total) who had been free of hypoglycemic medication for one week. RNA was hybridized to Affymetric HGU133plus2 platform following manufacturer's directions.