The Groucho/Tle coregulators are essential for early thymic progenitors and T-cell lineage specification
收藏NIAID Data Ecosystem2026-03-14 收录
官方服务:
资源简介:
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
应用场景:
创建时间:
2022-11-08
相关数据集
Characterization and analysis of long non-coding rna (lncRNA) in In Vitro - and Ex Vivo -derived cardiac progenitor cells
Recent advancements in cell-based therapies for the treatment of cardiovascular disease (CVD) show continuing promise for the use of transplanted stem and cardiac progenitor cells (CPCs) to promote ca
NIAID Data Ecosystem90
Matrix-dependent cardiac progenitor cell fate is instructed by the early regulation of YAP and Plk2
Although recent studies support regenerative potential based on cardiac progenitor cells (CPCs), it remains unclear what cues regulate CPC fate. Using 2- and 3D-culture models, we demonstrate that the
干细胞与再生医学数据中心2022-02-20 更新60
Fms-like tyrosine kinase 3 (Flt3) contributes to a receptor tyrosine kinase signature regulating the cardiac side population. Fms-like tyrosine kinase 3 (Flt3) contributes to a receptor tyrosine kinase signature regulating the cardiac side population
Fms-like tyrosine kinase 3 (Flt3) is a regulator of hematopoietic progenitor cells. It is a target of tyrosine kinase inhibitors (TKIs) used for acute myeloid leukemia treatment. Flt3 and its ligand (
NIAID Data Ecosystem30
The TH1 cell lineage-determining transcription factor T-bet supresses TH2 gene expression by redistributing GATA3 away from TH2 genes [ATAC-seq]. The TH1 cell lineage-determining transcription factor T-bet supresses TH2 gene expression by redistributing GATA3 away from TH2 genes [ATAC-seq]
Differentiation of progenitor cells into mature cell types is commonly associated with the expression of lineage-determining transcription factors (LD-TFs) specific to that lineage. In CD4+ T cells, T
NIAID Data Ecosystem70
Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells. Mus musculus
The interaction between extrinsic factors and intrinsic signal strength governs thymocyte development, but mechanisms linking them remain elusive. We report that mTORC1 couples microenvironmental cues
NIAID Data Ecosystem50



