Body weight, cortical area and lateral subchondral bone parameters in male mice.

Two-way ANOVA was used to assess the effects of surgery (control vs. surgery destabilizing the medial meniscus [DMM]) and genotype (Wnt16flox/flox vs. Cre-Wnt16flox/flox). The femoral cortical area was affected by genotype but not surgery, and no significant genotype by surgery interaction was detected. Body weight, lateral bone plate thickness, trabecular thickness and number was not affected by surgery, genotype or genotype by surgery interaction. BV/TV bone volume/tissue volume. Data are presented as mean ± SEM, P