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Serine synthesis pathway regulates cardiac differentiation from human pluripotent stem cells [RNA-seq]

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE290355
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资源简介:
Differences of metabolism-related gene expression profiles in human pluripotent stem cells (hPSCs) and hPSC-derived cardiomyocytes (hPSC-CMs) were analyzed and successfully identified. 253G4, 201B7, H9, NKX2-5eGFP/w cell lines were used for this experiments. hPSC-CM induction protocol was based on the modulation of the WNT signaling pathway. From Day 13 to Day 17, the cells were incubated with glucose- and glutamine-free medium supplemented with lactate for metabolic selection. hPSC-CMs obtained on Day 30 were used in the experiments.
创建时间:
2025-07-30
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