Summary of in-process characterizations of EV71 vaccine bulk produced from serum-free medium.
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ND: not determined.aTCID50 is the median tissue culture infective dose of EV71 that produces pathological cytopathic effects (CPE) in 50% of inoculated cell cultures.bTotal protein concentration was determined by the BCA protein assay.cVP2-specific epitope content was determined by Q-ELISA [19].dRecovery was calculated using the total VP2 epitope content at each step divided by the total VP2 epitope at the harvest stage.ediafiltration/concentration step.fgel-filtration chromatography purification.
创建时间:
2015-12-02



