Novel LncRNAs Networks and Targets in Myeloproliferative Neoplasms
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA703413
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资源简介:
Identify novel lncRNAs via RNA-seq in leukemic cell lines derived from BCR-ABL1-positive and JAK2-mutant myeloproliferative neoplasmsunder treatment with therapeutic tyrosine kinase inhibitors (TKI). The expression and sequence of novel LNC000093 were further validated in both leukemic cells and normal primary and pluripotent cells. In silico analysis combined with RNA-seq output supported the involvement of a putative miRNA-lncRNA-mRNA axis in these diverse tyrosine kinase-mediated pathways.
创建时间:
2021-02-21



