Anti-cancer drugs curaxins target the 3D genome organization
收藏NIAID Data Ecosystem2026-03-11 收录
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2019-04-08
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Top three gene ontology biological processes resulting from the analysis of differential regulated genes between antioxidant drugs and the respective solvent controls.
This analysis was performed using the DAVID program (see MM). Count indicates the number of genes belonging to the indicated gene ontology biological processes that we found regulated by a factor 2; %
NIAID Data Ecosystem60
Gene expression signatures in oridonin-treated WT and R878H hematopoietic stem cells. Gene expression signatures in oridonin-treated WT and R878H hematopoietic stem cells
Analysis of WT-Ctl v.s. WT-Ori and R878H-Ctl v.s. R878H-Ori hematopoietic stem cell (lineage-, c-kit+ Sca-1+ CD150+, CD34-). The four population of hematopoietic stem cell (HSC) were purified from the
NIAID Data Ecosystem60
Identification of genes involved in the anti-inflammatory effects of berberine in DNP-activated mouse MC/9 mast cells
Atopic dermatitis is a common chronic inflammatory skin disease characterized by infiltration of inflammatory cells, extensive pruritus and a clinical course of symptomatic flares and remissions. Berb
NIAID Data Ecosystem50
Integrated omics profiling reveals FOXA1 and Ku70/Ku80 as the direct target of ivermectin for prostate carcinogenic inhibition
Here, we show that ivermectin suppress prostate cancer progression by inhibiting AR signaling pathway and attenuate cellular DNA damage repair capacity. We applied an integrated omics profiling includ
NIAID Data Ecosystem60
CDK4/6 inhibitors induce repication stress to cause long-term cell cycle withdrawal
CDK4/6 inhibitors arrest the cell cycle in G1-phase. They are licenced to treat breast cancer and are also undergoing clinical trials against a range of other tumour types. To facilitate these efforts
NIAID Data Ecosystem60
