HUMAN TOPOISOMERASE I/DNA COMPLEX

HUMAN TOPOISOMERASE I/DNA COMPLEX Descriptor: DNA (5'-D(*AP*AP*AP*AP*AP*GP*AP*CP*TP*TP*AP*GP*AP*AP*AP*AP*AP*(BRU)P*(BRU)P*TP*TP*T)-3'), DNA (5'-D(*AP*AP*AP*AP*AP*TP*+UP*+UP*+UP*+UP*CP*+UP*AP*AP*GP*TP*CP*TP*TP*TP*+ UP*T)-3'), PROTEIN (DNA TOPOISOMERASE I) Authors: Redinbo, M.R, Stewart, L, Kuhn, P, Champoux, J.J, Hol, W.G. Deposit date: 1998-01-29 Release date: 1998-08-28 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science, 279, 1998