Analysis of allele-specific imbalance in discovery, validation, and combined sample sets.

*Risk Allele Lost refers to relative loss of risk allele compared to non-risk allele. Number in parentheses indicates percentage of total heterozygous samples showing relative loss of risk allele.†Non-risk Allele Lost refers to relative loss of non-risk allele compared to risk allele. Number in parentheses indicates percentage of total heterozygous samples showing relative loss of non-risk allele.§Total number of tumors with imbalance/total heterozygous samples (% of heterozygotes showing imbalance).‡Chi-squared statistical test, df = 1.∞Bonferroni correction for 16 multiple comparisons (original) or 3 multiple comparisons (validation, combined).