Correlation between SIAH2 expression and tumor grade.

Representative images of immunohistochemical analysis of SIAH2 in normal lung, well and poorly differentiated adenocarcinoma and squamous cell carcinoma. Occasional nuclear positivity in normal lung,

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SIAH2 protein expression correlates with expression of DYRK2.

(A) Representative images of adenocarcinoma or squamous cell carcinoma, and adjacent normal tissue stained with DYRK2 antibody (x100). (B) BEAS-2B cells were cultured with or without serum during 7 da

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Siah2 control on tumor environment

Understanding mechanisms underlying anti-tumor immunity is pivotal for improving immune-based cancer therapies. Here we demonstrate that growth of inoculated BRAF mutant melanoma cells was inhibited i

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