GWAS of Alzheimer's disease progression score
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https://figshare.com/articles/dataset/ADNI_FullSample_gwas_newPC_amyloid_assoc_linear/5603203/2
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Summary statistics for the three GWAS of 1517 Caucasian ADNI subjects described in Scelsi et al. - "Genetic study of multimodal imaging Alzheimer’s disease progression score implicates novel loci", manuscript under review at BRAIN (submission ID: BRAIN-2017-01752).1) FILE: ADNI_hippo_GWAS_EduCovar_NewUnrelated.assoc.linear; DESCRIPTION: GWAS (chromosomes 1-22) for bilateral hippocampal volume, correcting for age, sex, years of education, PC1-2, number of APOE4 alleles2) FILE: ADNI_amyloid_GWAS_EduCovar_NewUnrelated.assoc.linear; DESCRIPTION: GWAS (chromosomes 1-22) for cortical PET SUVR, correcting for age, sex, years of education, PC1-2, number of APOE4 alleles3) FILE: ADNI_DPS_GWAS_AmyHippoEduCovar_NewUnrelated.assoc.linear; DESCRIPTION: GWAS (chromosomes 1-22) for Disease Progression Score (DPS), correcting for age, sex, years of education, PC1-2, number of APOE4 alleles, baseline hippocampal volume, baseline PET SUVR4) FILE: ADNI_FullSample_chrX_newPC.hippo.EDUcovar.xstrat.linear; DESCRIPTION: Sex-stratified (Stouffer's method) association test of chromosome X for bilateral hippocampal volume, correcting for age, years of education, PC1-2, number of APOE4 alleles5) FILE: ADNI_FullSample_chrX_newPC.amyloid.EDUcovar.xstrat.linear; DESCRIPTION: Sex-stratified (Stouffer's method) association test of chromosome X for cortical PET SUVR, correcting for age, years of education, PC1-2, number of APOE4 alleles6) FILE: ADNI_FullSample_chrX_newPC.DPSupdate.amyhippoEDUcovar.xstrat.linear; DESCRIPTION: Sex-stratified (Stouffer's method) association test of chromosome X for DPS, correcting for age, years of education, PC1-2, number of APOE4 alleles, baseline hippocampal volume, baseline PET SUVR
提供机构：
figshare
创建时间：
2017-11-15
