XIAP in complex with small molecule
收藏Protein Data Bank Japan2024-05-08 更新2026-03-21 收录
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XIAP in complex with small molecule Descriptor: 1-[6-[(4-fluorophenyl)methyl]-5-(hydroxymethyl)-3,3-dimethyl-2~{H}-pyrrolo[3,2-b]pyridin-1-yl]-2-[(2~{R},5~{R})-5-methyl-2-[[(3~{R})-3-methylmorpholin-4-yl]methyl]piperazin-4-ium-1-yl]ethanone, E3 ubiquitin-protein ligase XIAP, SODIUM ION, ... Authors: Williams, P.A. Deposit date: 2017-08-14 Release date: 2018-06-27 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.31 Å) Cite: ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNF alpha-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth. Mol. Cancer Ther., 17, 2018
创建时间：
2017-08-14
