Peste des petitsruminants virus (PPRV) neutralizing antibody titers and lymphocyte proliferation responses in goats immunized with PPRV virus-like particles (VLPs) or native PPRV particles.

PPRV neutralizing antibody titers in goats immunized with the PPRV VLPs, PPRV, and PBS. Serum samples were collected at weeks 0,1,2, 3, 5, 7, 11, and 15 after primary vaccination. Proliferation responses of peripheral blood lymphocytes in goats were tested at week 2 after boost immunization.PBS = phosphate-buffered saline, as negative control; PPRV = Peste des petits virus; VLP = virus-like particles.*Different superscript letters indicate that the differences were significant (p0.05). (according to one-way ANOVA, using GraphPad).