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Light chain amyloid fibrils from multiple myeloma patient (case 1), abdominal fat biopsy

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NIAID Data Ecosystem2026-05-10 收录
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In this study, we used minimally invasive abdominal fat biopsies routinely performed in clinical practice, to obtain amyloid fibrils from living MM patient. Using cryo-electron microscopy (cryo-EM) and mass spectrometry (MS), we successfully determined the sequence and high-resolution structure of light chain fibril polymorphs.

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2025-12-25
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