Depth of sequencing coverage of matched sample set (N = 6 samples (per method)).

Percent of on-target bases (y-axis) covered at a given sequence depth (x-axis). On target percentage calculated as the fraction of nucleotide bases falling on targeted regions divided by the total number of nucleotides mapping anywhere in the genome. Thick lines represent average coverage for each platform (Agilent Surelect = blue circles; Nimblegen SeqCap = green triangles; Raindance parallel PCR = red diamonds). Dashed lines represent two standard deviations above and below the average for each platform.