Order of designs by predicted binding score.

Numbers of correctly ranked design mutation pairs with large affinity difference. All mutation pairs for which there is an affinity difference of at least 50-fold are investigated. All design pairs with these mutations (i.e. for each of these pairs there are as many design pairs as scaffold crystal structures) are checked, if the order of the mutations by total score or binding score is the same order as by affinity. A cell shows the number of correctly ordered design pairs, and the number of all design pairs. The mean for this part is calculated by scaling the percentage of a test case by the number of mutation pairs (i.e. NOT by design pairs, which would bias the value too much towards test cases with many crystal structures).