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The Treg Signaling network depicts the causal mechanisms that are activated in CD4+ Foxp3+ regulatory T-cells following T-cell receptor (TCR) ligation. Expanding on these processes, the network highlights the chemokines secreted by macrophages and dendritic cells, as well as the cognate T-cell receptors, involved in mediating T-cell recruitment to compromised lung tissue during COPD development.

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2021-04-15
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