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Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with new carbapenem drug T203

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of the Mycobacterium tuberculosis L,D-transpeptidase-2 (LdtMt2) with new carbapenem drug T203 Descriptor: (2R,3R)-3-methyl-4-(2-oxidanylidene-2-propan-2-yloxy-ethyl)sulfanyl-2-[(2R)-3-oxidanyl-1-oxidanylidene-butan-2-yl]-2,3-dihydro-1H-pyrrole-5-carboxylic acid, (4R,5S,6S)-6-((R)-1-hydroxyethyl)-3-((2-isopropoxy-2-oxoethyl)thio)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, GLUTAMIC ACID, ... Authors: Kumar, P, Lamichhane, G. Deposit date: 2021-07-02 Release date: 2022-05-11 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Allosteric cooperation in beta-lactam binding to a non-classical transpeptidase. Elife, 11, 2022
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2021-07-02
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