官方服务:
资源简介:
This data shows the altered gene after injection of a-synuclein fibril into the mouse brain.
应用场景:
创建时间:
2021-01-27
相关数据集
Table2_Galectin-3 Deletion Reduces LPS and Acute Colitis-Induced Pro-Inflammatory Microglial Activation in the Ventral Mesencephalon.docx
Parkinson’s disease is a highly prevalent neurological disorder for which there is currently no cure. Therefore, the knowledge of risk factors as well as the development of new putative molecular targ
NIAID Data Ecosystem70
Effect of terminal ischemia/anoxia on the ECS diffusion parameters, ADC W and extracellular K + concentration in α-syn +/+ and α-syn −/− mice in vivo .
The values are presented as mean ± S.E.M. Asterisks (*-p<0.05; **-p<0.01; ***-p<0.001) indicate significant differences between the values in α-syn +/+ and α-syn −/− animals; crosshatches (#-p<0.05; #
NIAID Data Ecosystem40
Sexually dimorphic microglia responses to MPTP, inflammation and gut microbiome profiles in a progressive monkey model of Parkinsons disease. primate metagenome
Our analyses revealed sex-dependent sensitivity to MPTP that resulted in early microglial activation by PET, acute plasma IL-6 and CSF TNF, and earlier Parkinsonism as measured by motor deficits in ma
NIAID Data Ecosystem30
THE HUMAN BRAIN MICROBIOME IN HEALTH AND PARKINSONS's DISEASE MUCH ADO ABOUT NOTHING
Background: Several studies of PD and AD patients' brains and experimental models indicate the presence of inflammatory processes in both diseases. This was recently linked to remnants of poly-microbi
NIAID Data Ecosystem60
Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease. Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson disease
Neuroinflammation and accumulation of alphα-synuclein (α-syn) are core features of Parkinson disease (PD). We found that α-syn-induced neuroinflammation is driven by antigen presentation from CNS resi
NIAID Data Ecosystem40



