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Crystal structure of human WEE1 kinase domain in complex with PD-166285

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of human WEE1 kinase domain in complex with PD-166285 Descriptor: 1,2-ETHANEDIOL, 6-(2,6-dichlorophenyl)-2-({4-[2-(diethylamino)ethoxy]phenyl}amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one, CHLORIDE ION, ... Authors: Zhu, J.-Y, Schonbrunn, E. Deposit date: 2017-03-31 Release date: 2017-08-23 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors. J. Med. Chem., 60, 2017

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2017-03-31
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