Genome-wide localization of RNA polymerase II and histone modifications in diffuse intrinsic pontine glioma cells in response to CDK9 inhibition

We report the application of chromatin immunoprecipitation for high-thoughput profiling of RNA polymerase II and histone modifications (H3K27me3 and H3K27ac) in diffuse intrinsic pontine glioma cells (DIPG) in response to CDK9 inhibition Overall design: Examination of the localization of RNA polymerase II and two different histone modifications in DIPG cells