Specificity of EGCG inhibition.

The % activity is the normalized signaling activity by the innate immune receptor or the adaptor IPS-1 observed in the presence of 2 µM of EGCG and Clemizole in the reporter assay using HEK293T cells. The numbers correspond to the mean of the experiment and the standard deviation is in parenthesis. Analysis was performed using firefly luciferase reporter driven by IFN-β, NF-κB or ISRE promoters as mentioned above the % activity.