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Beta-lactamase VIM-2 in complex with (2R)-1-(2-Benzyl-3-mercaptopropanoyl)piperidine-2-carboxylic acid

NIAID Data Ecosystem2026-05-02 收录

蛋白质-配体复合物结构

细菌耐药性机制

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Beta-lactamase VIM-2 in complex with (2R)-1-(2-Benzyl-3-mercaptopropanoyl)piperidine-2-carboxylic acid

应用场景：

创建时间：

2024-05-08

细菌耐药性机制

细菌转录组学

RNA-Seq on common bacterial pathogens in the presence vs absence of a variety of antibiotics. Two susceptible and two resistant isolates were exposed to antibiotics in laboratory culture, total RNA wa

NIAID Data Ecosystem40

DataSheet_4_Persistent ciprofloxacin exposure induced the transformation of Klebsiella pneumoniae small colony variant into mucous phenotype.csv

细菌表型转换

细菌耐药性机制

IntroductionSmall colony variant (SCV) is a bacterial phenotype closely related to persistent and recurrent infections. SCVs are mutations that occur within bacterial populations, resulting in a chang

NIAID Data Ecosystem00

Table 1_The dltC gene contributes to polyhexamethylene biguanide resistance in Staphylococcus aureus.docx

细菌耐药性机制

聚六亚甲基双胍耐药性

As the efficacy of conventional antibiotics continues to decline due to antibiotic resistance, there is an urgent need for alternative antimicrobial strategies. Polyhexamethylene biguanide (PHMB), a c

NIAID Data Ecosystem00

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

细菌耐药性机制

细菌代谢干预治疗

Exogenous pyruvate promotes gentamicin uptake to kill antibiotic-resistant Vibrio alginolyticus

integrated proteome resources30

Development and application of CRISPR/Cas9-assisted genome-editing tools for comprehensive investigation the role of efflux pumps in Mycobacterium abscessus

细菌耐药性机制

外排泵毒力功能

Using CRISPR/Cas9-assisted genome-editing tools, we constructed 68 efflux pump mutants of M. abscessus and investigated their roles in drug resistance and virulence. We found that different efflux pum

NIAID Data Ecosystem00

Beta-lactamase VIM-2 in complex with (2R)-1-(2-Benzyl-3-mercaptopropanoyl)piperidine-2-carboxylic acid

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