Supplementary data

This spreadsheet holds the data used in the manuscript. The following list explains column names: (see ReadMe.doc for more information).subject: Each subject has a unique letter identifierAnonID: Anonymous IDGroup: PD or ControlCategory: Cognitive category. PDN = PD with normal cognition, PD-MCI = PD with Mild Cognitive Impairment, PDD = PD with dementia, HC = healthy control.Category_HC-MCI: Cognitive category. However, this time 3 controls classified as MCI are identified (C-MCI). Convert: The status of each individual at 1 year follow up. HC = healthy control, Stable = Did not develop dementia, Convert = Developed dementia at 1 year. Age_at_scan_years: Age at assessment/scanAge_base: Age as study entrytime_btw_scans_years: Time between scans measured in years.Female: 0 = male, 1 = femaleEducation: years of educationFU_1year: 1st or 2nd scantime: assessment time, either baseline (study entry) or follow up (~ 1year).time.y: time, in years, of follow up.GM_order.diff.and.avg: Subject order of the 4D files associated with grey matter (swarate_GM_44.nii.gz, swavg_GM_44.nii.gz).Exclude.motion.T1: T1 images excluded due to motion at Y0 or Y1.TBSS_order.diff.and.avg: Order of the 4D image files associated with DTI and TBSS.ASL_order.diff: Subject order of the 4D image file (sdiff_wecqCBF_43.nii.gz:).ASL_order_avg.part1: Subject order of the 4D image files (demeaned_swecqCBF_43_base_part1.nii.gz, savg_wecqCBF_43_part1.nii.gz).ASL_order_avg.part2: Subject order of the 4D image files (demeaned_swecqCBF_43_base_part2.nii.gz, savg_wecqCBF_43_part2.nii.gz).SIENA: % brain change between scans. Values only at baseline (first timepoint).DTI relative motion: average relative motion between adjacent diffusion volumes (see manuscript for details).mean FA/MD/L1/RD: mean FA /MD/L1/RD values along the white matter skeleton CBF_gm: mean grey matter perfusion (ml/100g/min), including cortex and subcortical grey.diff.FA.Y0-Y1 (same for MD/CBF): raw difference between mean FA at Y0 and Y1.per.diff.FA.Y0-Y1 (same for MD/CBF): percent difference between mean FA at Y0 and Y1.per.diff.year.FA.Y0-Y1 (same for MD/CBF): percent difference between mean FA at Y0 and Y1, divided by the time between Y0 and Y1.MoCa: Montreal cognitive assessment—global cognitive screen.UPDRS Part 3: Unified Parkinson’s disease rating scale, part 3, the motor score (only scores for PD participants).LED: Levodopa equivalent dose.Attention Total: average z score for tests in the domain of attention, working memory, and processing speed. Executive Function Total: average z score for tests in the domain of executive function.Visuo-Total: average z score for tests in the domain of visuospatial/visuoperceptual function.Language all Domains: average z score for tests in the domain of Language. Total all Domains: global cognitive score: average z score for the domain scores (attention, executive function, learning & memory, and visuospatial/perceptual)