CCR4
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1347259
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资源简介：
The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine - MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. [provided by RefSeq, Jul 2008]
该基因编码的蛋白质属于G蛋白偶联受体家族。它是一种针对CC趋化因子-MIP-1、RANTES、TARC和MCP-1的受体。趋化因子是一类结构上相关的小型多肽分子群，调节各类白细胞的细胞迁移。趋化因子在免疫系统的发展、稳态和功能中发挥着根本性作用，并对中枢神经系统的细胞以及参与血管生成或血管收缩的血管内皮细胞产生效应。 [由RefSeq提供，2008年7月]
提供机构：
Rat Genome Database
