Uncertainty bounds and hypothesis testing of the post-peak seroepidemiological studies of influenza (H1N1-2009).

†Sample size refers to the number of enrolled subjects to measure the seroprevalence after observing an epidemic peak. Proportion infected is given by the proportion after observing peak minus the proportion before the peak in Table 1.‡95% confidence intervals (CI) show lower and upper confidence intervals of the proportion. The 95% CI of binomial proportion is derived from a normal approximation to binomial distribution, while the 95% CI of final size is similarly derived from the Wald method employing asymptotic convergence result of final size distribution.§After peak column represents if the sampling took place longer than 1 month after observing the highest incidence of cases.¥Vaccination column represents if a population-wide vaccination campaign of H1N1-2009 took place prior to the sampling.$p-values are based on two-sided Wald test employing the approximate standard error of final epidemic size.R, the estimated reproduction number in Mexico against which we would like to test our hypothesis; CV, the coefficient of variation of the generation time. Significant difference is indicated by * mark followed by p-value.