Synthesis of l-<i>β</i>-3‘-Deoxy-3‘,3‘-difluoro-4‘-thionucleosides
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An efficient route to l-β-3‘-deoxy-3‘,3‘-difluoro-4‘-thionucleosides, thio-containing analogues of highly bioactive gemcitabine, is described. Our synthesis highlighted the installation of the thioacetyl group in high efficiency and construction of 3-deoxy-3,3-difluorothiofuranose skeleton in a novel method.
创建时间：
2016-02-29
