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Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor

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Protein Data Bank Japan2023-09-20 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4r76
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Structure of the m17 leucyl aminopeptidase from malaria complexed with a hydroxamic acid-based inhibitor Descriptor: 3-amino-N-{(1R)-2-(hydroxyamino)-2-oxo-1-[4-(1H-pyrazol-1-yl)phenyl]ethyl}benzamide, CARBONATE ION, M17 family aminopeptidase, ... Authors: Drinkwater, N, Mcgowan, S. Deposit date: 2014-08-27 Release date: 2014-10-29 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Two-Pronged Attack: Dual Inhibition of Plasmodium falciparum M1 and M17 Metalloaminopeptidases by a Novel Series of Hydroxamic Acid-Based Inhibitors. J.Med.Chem., 57, 2014
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2014-08-27
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