One-Pot, Two-Step Synthesis of Imidazo[1,2‑<i>a</i>]benzimidazoles via A Multicomponent [4 + 1] Cycloaddition Reaction
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资源简介：
A one-pot, two-step synthesis of imidazo[1,2-a]benzimidazoles has been achieved by a three-component reaction of 2-aminobenzimidazoles with an aromatic aldehyde and an isocyanide. The reaction involving condensation of 2-aminobenzimidazole with an aldehyde is run under microwave activation to generate an imine intermediate under basic conditions which then undergoes [4 + 1] cycloaddition with an isocyanide.
创建时间：
2013-10-14
