PDE10a Crystal Structure Complexed with Novel Inhibitor
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PDE10a Crystal Structure Complexed with Novel Inhibitor Descriptor: 2-{1-[5-(6,7-dimethoxycinnolin-4-yl)-3-methylpyridin-2-yl]piperidin-4-yl}propan-2-ol, SULFATE ION, ZINC ION, ... Authors: Chmait, S, Jordan, S, Zhang, J. Deposit date: 2012-01-18 Release date: 2012-03-21 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.07 Å) Cite: Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Bioorg.Med.Chem.Lett., 22, 2012
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2012-01-18
