Benefit of a second opinion, intrapulmonary metastases or multiple primary tumors?. Homo sapiens

The presence of bilateral pulmonary nodules in lung cancer usually means distant metastases (M1a). We present an extraordinary example that challenges to look beyond this classification, and illustrates the potential benefits of a multidisciplinary re-evaluation in such a case. Overall design: FFPE DNA from a patient with three primary tumors. Test samples were compared to normal tissue.