Structure of MDM2 with low molecular weight inhibitor with aliphatic linker.
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Structure of MDM2 with low molecular weight inhibitor with aliphatic linker. Descriptor: 4-({6-[(6-chloro-3-{1-[(4-chlorophenyl)methyl]-4-(4-fluorophenyl)-1H-imidazol-5-yl}-1H-indole-2-carbonyl)oxy]hexyl}amino)-4-oxobutanoic acid, E3 ubiquitin-protein ligase Mdm2 Authors: Twarda-Clapa, A, Kubica, K, Guzik, K, Dubin, G, Holak, T.A. Deposit date: 2016-04-06 Release date: 2017-05-17 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (1.85 Å) Cite: 1,4,5-Trisubstituted Imidazole-Based p53-MDM2/MDMX Antagonists with Aliphatic Linkers for Conjugation with Biological Carriers. J. Med. Chem., 60, 2017
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2016-04-06
