Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog
收藏Protein Data Bank Japan2024-02-21 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3h3c
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of PYK2 in complex with Sulfoximine-substituted trifluoromethylpyrimidine analog Descriptor: 4-{[4-{[(1R,2R)-2-(dimethylamino)cyclopentyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}-N-methylbenzenesulfonamide, Protein tyrosine kinase 2 beta, SULFATE ION Authors: Han, S, Mistry, A. Deposit date: 2009-04-16 Release date: 2009-05-26 Last modified: 2024-02-21 Method: X-RAY DIFFRACTION (2 Å) Cite: Sulfoximine-substituted trifluoromethylpyrimidine analogs as inhibitors of proline-rich tyrosine kinase 2 (PYK2) show reduced hERG activity. Bioorg.Med.Chem.Lett., 19, 2009
创建时间：
2009-04-16
