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Additional file 1 of Identifying genes associated with brain volumetric differences through tissue specific transcriptomic inference from GWAS summary data

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Figshare2022-09-29 更新2026-04-08 收录
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https://springernature.figshare.com/articles/dataset/Additional_file_1_of_Identifying_genes_associated_with_brain_volumetric_differences_through_tissue_specific_transcriptomic_inference_from_GWAS_summary_data/21228856/1
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Additional file 1: This file contains the following supplementary tables. Supplemental Table S1a. Gene findings from the UKB analysis, where TBV is the trait of interest. Shown in the table are the p-values. Supplemental Table S1b. Gene findings from the ENIGMA2 analysis, where ICV is the trait of interest. Of note, this is a targeted analysis which only examines the gene findings from the previous UKB analysis. In other words, we were looking for which TBV-associated genes were also significantly associated with ICV. Shown in the table are the p-values. Supplemental Table S2. Among 10 genes discovered in our study, 9 of them (except FAM215B) are significantly associated with TBV in the gene-based association analysis of the original UKB GWAS (Zhao et al.). Supplemental Table S3. Results of enrichment analysis of 10 discovered genes on Gene Ontology Biological Processes. Supplemental Table S4. Results of enrichment analysis of 10 discovered genes on Gene Ontology Molecular Functions.
提供机构:
Bao, Jingxuan; Kim, Dokyoon; Shen, Li; Mai, Hung; Thompson, Paul M.
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2022-09-29
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