SupplementaryMaterials_PG

Figshare2019-04-18 更新2026-04-29 收录

计算细胞去卷积

关节炎病理机制

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Supplementary Materials for Computational Deconvolution of Synovial Tissue Cellular Composition: Presence of adipocytes in synovial tissues decreased during arthritis pathogenesis and progression

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2019-04-18

Matrix-mediated activation of fibroblasts in rheumatoid arthritis

关节炎病理机制

细胞外基质-细胞相互作用

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease affecting synovial joints and leading to cartilage damage and bone loss. This destruction is promoted by activated fibroblast-like synov

NIAID Data Ecosystem80

Single cell RNA sequencing on synovium, meniscus and cartilage of rheumatoid arthritis

关节炎病理机制

单细胞转录组学

Rheumatoid arthritis (RA) induced destruction of knee joints is a common cause of total knee arthroplasty (TKA). Under single cell RNA sequencing generated by 10x Genomics, we identified CD142+ synovi

NIAID Data Ecosystem60

Carbonic Anhydrase 2 is Required for Maintaining Metabolic Homeostasis of Human Articular Chondrocytes

软骨细胞代谢调控

关节炎病理机制

Objective: To examine the role of carbonic anhydrase II (CA2 gene), the most efficient isoform in the CA family of zinc-containing metalloenzymes, in chondrocyte metabolism. Methods: CA2 expression wa

NIAID Data Ecosystem40

C/EBPβ Promotes Transition from Proliferation to Hypertrophic Differentiation of Chondrocytes through Transactivation of p57 Kip2

软骨细胞分化调控

关节炎病理机制

BackgroundAlthough transition from proliferation to hypertrophic differentiation of chondrocytes is a crucial step for endochondral ossification in physiological skeletal growth and pathological disor

NIAID Data Ecosystem60

Prominent expression of mRNA for proinflammatory cytokines in synovium in patients with juvenile rheumatoid arthritis or chronic Lyme arthritis

关节炎病理机制

细胞因子表达分析

OBJECTIVE: To examine the cytokine profiles in synovium of patients with juvenile rheumatoid arthritis (JRA) or Lyme arthritis, 2 chronic inflammatory arthritides that affect children. METHODS

Figshare2016-01-11 更新40

SupplementaryMaterials_PG

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