Compressed sensing (CS), mutual information (MI), and ensemble classifier predictions of HIV-1 Env positions constituting bnMAb epitopes for PGT 127, 128, and 130.
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https://figshare.com/articles/dataset/_Compressed_sensing_CS_mutual_information_MI_and_ensemble_classifier_predictions_of_HIV_1_Env_positions_constituting_bnMAb_epitopes_for_PGT_127_128_and_130_/866285
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The experimentally identified positions are defined as those at which alanine point mutations were observed to increase the measured IC50 of the mutant by more than 30-fold relative to that of the wild type JR-CSF. Alanine scans were performed as part of the present work for PGT 143 and 145; data for PGT 121–135 were taken from Ref. [51].
Footnote: See footnote to Table 1.
创建时间:
2013-12-02



