Supplemental methods on patient recruitment and sample processing.

Table A in S1 File. Age and gender matched study participants from Dublin. This table reports the age, gender and ethnicity of the subsets of patients (n = 20 per groups) with IPAH and CTD-PAH from the Dublin cohort, together with matched controls, used to measure plasma CXCL12 concentrations. These subjects CXCL12 concentrations are graphed in Fig 1. Data are presented as median (lower-upper quartile). Table B in S1 File. Age and gender matched study participants from Sheffield. This table reports the age, gender and ethnicity of the subsets of patients (n = 19 or 21 per groups) with IPAH and CTD-PAH from the Sheffield cohort, together with matched controls from Dublin, used to measure plasma CXCL12 concentrations. These subjects CXCL12 concentrations are graphed in Fig 2. Data are presented as median (lower-upper quartile). (DOCX)