Mre11 Rad50 binding domain in complex with Rad50 and AMP-PNP

NIAID Data Ecosystem2026-05-01 收录

蛋白质复合物结构

DNA损伤修复

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Mre11 Rad50 binding domain in complex with Rad50 and AMP-PNP

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2023-09-13

Discovery of Isaindigotone Derivatives as Novel Bloom’s Syndrome Protein (BLM) Helicase Inhibitors That Disrupt the BLM/DNA Interactions and Regulate the Homologous Recombination Repair

DNA损伤修复

抗癌药物设计

Homologous recombination repair (HRR), a crucial approach in DNA damage repair, is an attractive target in cancer therapy and drug design. The Bloom syndrome protein (BLM) is a 3′–5′ DNA helicase that

NIAID Data Ecosystem40

Structure of Tne2 in complex with Tni2

蛋白质复合物结构

结构生物学

Structure of Tne2 in complex with Tni2

NIAID Data Ecosystem20

Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog

冷冻电镜结构解析

蛋白质复合物结构

Cryo-EM structure of murine Dispatched in complex with Sonic hedgehog Descriptor: (2S)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(hexanoyloxy)propyl hexanoate, 2-acetamido-2-deoxy-beta-D-gluco

Protein Data Bank Japan2024-11-13 更新00

WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair

DNA损伤修复

DNA相互作用

Mass spectrometry data relating to Figure 1 and Table S1.

NIAID Data Ecosystem40

Cryo-EM structure of SHOC2-PP1c-MRAS holophosphatase complex

冷冻电镜结构解析

蛋白质复合物结构

Cryo-EM structure of SHOC2-PP1c-MRAS holophosphatase complex Descriptor: CHLORIDE ION, GUANOSINE-5'-TRIPHOSPHATE, Leucine-rich repeat protein SHOC-2, ... Authors: Fuller, J.R, Hajian, B, Lemke, C, Kwo

Protein Data Bank Japan2024-06-12 更新00

Mre11 Rad50 binding domain in complex with Rad50 and AMP-PNP

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