Raptor determines β-cell identity and plasticity independent of metabolic state. Raptor determines β-cell identity and plasticity independent of metabolic state

In this study, we employed RNA-seq technology to identify the exact role of mTORC1 on β-cell identity and plasticity. Overall design: β cell specific Raptor deficiency induced gene expression from purified β cells in mice with or without insulin pellets was measured at 4 weeks after the pellet implanted. β cells from WT mice were set as controls.