Cystic fibrosis patients suffer from chronic lung infections that require long-term antibiotic therapy. Pseudomonas readily evolve resistance, rendering antibiotics ineffective. In vitro experiments s

NIAID Data Ecosystem30

Comparative Genomics of Isolates of a Pseudomonas aeruginosa Epidemic Strain Associated with Chronic Lung Infections of Cystic Fibrosis Patients

囊性纤维化肺部感染

细菌基因组学

Pseudomonas aeruginosa is the main cause of fatal chronic lung infections among individuals suffering from cystic fibrosis (CF). During the past 15 years, particularly aggressive strains transmitted a

NIAID Data Ecosystem20

Using RNA Seq to identify a CF habitat specific transcriptional profile

病原体转录组

囊性纤维化肺部感染

Purpose: The goal of this study was to use RNA Seq to explore whether and to what extent genetic heterogeneity would shape the transcriptional profile in the environment of the CF lung Methods : mRNA

NIAID Data Ecosystem50

DataSheet_2_An Innovative Protocol for Metaproteomic Analyses of Microbial Pathogens in Cystic Fibrosis Sputum.pdf

临床元蛋白质组学

囊性纤维化肺部感染

Hallmarks of cystic fibrosis (CF) are increased viscosity of mucus and impaired mucociliary clearance within the airways due to mutations of the cystic fibrosis conductance regulator gene. This facili

NIAID Data Ecosystem30

Chronically Infected Cystic Fibrosis Lungs Genome Sequencing. Pseudomonas aeruginosa

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