Inactivation of PLC beta

PLC-beta1 is a GTPase-activating protein (GAP) for Gq-alpha, exchanging GTP for GDP and releasing the alpha subunit to cycle back to the membrane and reassociate with the beta-gamma subunits. Between itself and the receptor, they regulate the amplitude of the PLC signal and the rates of signal initiation and termination.

PLC-beta1是一种针对Gq-alpha的GTPase激活蛋白（GAP），其功能在于将GTP与GDP进行交换，从而释放α亚基，使其循环回到质膜并与β-γ亚基重新结合。在此过程中，PLC-beta1与其受体共同调节PLC信号的幅度以及信号启动和终止的速率。