Sm core proteins play an essential role in the formation of small nuclear ribonucleoprotein particles (snRNPs) by binding to small nuclear RNAs and participating in a network of protein interactions.
* Activation of the mutants are displayed in multiple degrees such as +++ (very strong) ∼ ± (weak). BTA: basal transactivation function. TLP-SF: TLP-stimulated function examined by over-expression ass
Additional file 18: Figure S17. Subgrouping classifier scores reveal relationships between mutations within cancer genes. We dissected the scores returned by our mutation classifiers for mutations wit