Cavefish Mount a Rapid and Sustained Regenerative Response Following Skeletal Muscle Injury

This study seeks to investigate the temporal, genome-wide response of skeletal muscle following cardiotoxin injection within the skeletal muscle of the Astyanax mexicanus – comprised of the river-dwelling surface fish and troglobitic cavefish – providing novel insights into the evolutionary consequence of skeletal muscle regernation. Overall design: Skeletal muscle from cavefish and surface fish were collected at multiple timepoints spanning a 24-hour cycle. Three fish were used at each timepoint.