Organocatalytic Sequential α-Amination/Corey–Chaykovsky Reaction of Aldehydes: A High Yield Synthesis of 4-Hydroxypyrazolidine Derivatives
收藏Figshare2016-02-20 更新2026-04-29 收录
下载链接：
https://figshare.com/articles/dataset/Organocatalytic_Sequential_Amination_Corey_Chaykovsky_Reaction_of_Aldehydes_A_High_Yield_Synthesis_of_4_Hydroxypyrazolidine_Derivatives/2521609
下载链接
链接失效反馈官方服务：
资源简介：
A tandem reaction of in situ generated α-amino aldehydes with dimethyloxosulfonium methylide under Corey–Chaykovsky reaction conditions proceeds efficiently to give 4-hydroxypyrazolidine derivatives in high yields with excellent enantio- and diastereoselectivities. This organocatalytic sequential method provides for the efficient synthesis of anti-1,2-aminoalcohols, structural subunits present in several bioactive molecules as well.
创建时间：
2016-02-20
