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Transcriptome differences in HCC infiltrated CD8+ T cells in effector and exhaustion state. Transcriptome differences in HCC infiltrated CD8+ T cells in effector and exhaustion state

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NIAID Data Ecosystem2026-03-11 收录
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CD8+ T cells isolated from HCC tissue were divided into three groups: PD1-TIM3- CD8+ TILs, exhibiting full effector function; PD1-intTIM3+ CD8+ TILs, exhibiting partial exhaustion; and PD1-hiTIM3+ CD8+ TILs, exhibiting severe exhaustion, as reflected by the differences in their ability to produce effector cytokines respectively. Transcriptome sequence analysis was performed to investigate the gene expression profile was performed.

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2020-01-08
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