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A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS)

NIAID Data Ecosystem2026-03-11 收录

骨髓增生异常综合征

染色体易位表观遗传学

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE118648 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-12-02

基因表达

骨髓增生异常综合征

Research and Analysis of Differential Gene Expression in CD34 Hematopoietic Stem Cells in Myelodysplastic Syndromes

DataCite Commons2024-10-24 更新290

MDS in Humanized Mice. MDS in Humanized Mice

骨髓增生异常综合征

异种移植基因组学

This study was to develop a faithful pre-clinical MDS patient-derived xenotransplantation model in cytokine-humanized immunodeficient "MISTRG" mice. We performed targeted genome sequencing on bone mar

NIAID Data Ecosystem70

Gene expression profile of HSPC with cell-intrinsic innate immune signaling activation after LPS treatment

造血干细胞基因表达

骨髓增生异常综合征

The underlying mechanisms responsible for the competitive advantage of MDS HSPC in an inflammatory milieu remains poorly defined. Here, we show that MDS HPSC are protected from low-grade chronic infla

NIAID Data Ecosystem50

Supplementary Material for: Copper Deficiency Mimicking Myelodysplastic Syndrome: Zinc Supplementation in the Setting of COVID-19

铜缺乏症

骨髓增生异常综合征

While copper deficiency is rare, it can have serious consequences, including pancytopenia and neuropathy. This treatable vitamin deficiency can present very similarly to myelodysplastic syndrome (MDS)

DataCite Commons2023-07-22 更新80

SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes

骨髓增生异常综合征

SF3B1突变剪接异常

SF3B1 is the most frequently mutated RNA splicing factor in cancer, including in ~25% of myelodysplastic syndromes (MDS) patients. SF3B1-mutated MDS, which is strongly associated with ringed siderobla

NIAID Data Ecosystem50

A Distinct Epigenetic Program Underlies the 1;7 Translocation in Myelodysplastic Syndromes (MDS)

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