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资源简介：
colorectal cancer, 5-FU resistance
应用场景：
创建时间：
2021-01-22
相关数据集
Gene expression profile of H187-63AR, an ABT-737 resistant derivative of H187. Homo sapiens
ABT-737 is a highly potent small molecule inhibitor of Bcl-2 which has demonstrated efficacy in preclinical studies. To identify factors which mediate ABT-737 sensitivity we created an ABT-737-resista
NIAID Data Ecosystem80
Melanoma therapeutic strategies that select against resistance by exploiting MYC-driven evolutionary convergence. Homo sapiens
Diverse pathways can drive resistance to BRAF and MEK inhibitors in BRAF mutant melanoma, suggesting that durable control of resistance will be a major challenge. By combining statistical modeling of
NIAID Data Ecosystem70
Acquired resistance to combined BET and CDK4/6 inhibition in triple-negative breast cancer [RNA-Seq]
BET inhibitors are promising therapeutic agents for the treatment of triple-negative breast cancer (TNBC), but the rapid emergence of resistance necessitates investigation of combination therapies and
NIAID Data Ecosystem20
Reliance upon ancestral mutations is maintained in colorectal cancers that heterogeneously evolve during targeted therapies. Targeting WNT pathway in MAPK resistant CRC
Attempts at eradicating metastatic cancers with targeted therapies are limited by the emergence of resistant sub-clones bearing heterogeneous (epi)genetic changes. Here we use colorectal cancer to tes
NIAID Data Ecosystem70
Additional file 3 of Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer
Additional file 3.
NIAID Data Ecosystem30
